BDBM31985 Dipeptidyl nitrile inhibitor, 18

SMILES Cc1nn(C)cc1C(=O)N[C@@H](Cc1cccc(Cl)c1)C(=O)NCC#N

InChI Key InChIKey=MYBHYCWWPQBNSP-HNNXBMFYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31985   

TargetProcathepsin L [114-333,T223A](Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM31985(Dipeptidyl nitrile inhibitor, 18)
Affinity DataIC50:  1.26E+3nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed